Advil caplets deliver powerful pain relief with the strength to last for hours. For over 30 years, patients and doctors have trusted Advil to deliver powerful relief from many kinds of acute pain, including: headache, back pain, muscle aches, minor arthritis pain and other joint pain. Use as directed. When taking other medications, it is important to understand the ingredients to reduce the risk of drug interactions and adverse events. You should not take more than the recommended dose because it will increase the risk of side effects. To maximize the benefit and reduce risk, it is important to use over-the-counter medicines responsibly according to the label and speak with a doctor or pharmacist if you have any questions.